ODCs

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1 OMIM reference -
1 associated gene
2 signs/symptoms

PROTEIN INTERACTIONS: 1

16 OMIM references -
4 associated genes
No signs/symptoms info

Syndactyly type 8

Early-onset autosomal dominant Alzheimer disease


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FGF16	(0.56)	APP

Citations in the biomedical literature:

Syndactyly type 8		Early-onset autosomal dominant Alzheimer disease
	Synonym(s): - Fusion of metacarpals 4 and 5		Synonym(s): - EOFAD - Early-onset familial autosomal dominant Alzheimer disease - Familial Alzheimer disease

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: - Average age onset: - Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: adulthood Average age of death: adult Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 16 OMIM references - No MeSH references

Syndactyly type 8
	Very frequent - Metacarpal anomalies / Archibald's sign - X-linked recessive inheritance
Early-onset autosomal dominant Alzheimer disease
(no data available)